Vitamin D Supplementation Impacts Calcium and Phosphorus Metabolism in Piglets Fed a Diet Contaminated with Deoxynivalenol and Challenged with Lipopolysaccharides
- Date de publication : 2023-06-13
Référence
Sauvé B., Chorfi Y., Létourneau-Montminy M.-P., Guay F., 2023. Vitamin D Supplementation Impacts Calcium and Phosphorus Metabolism in Piglets Fed a Diet Contaminated with Deoxynivalenol and Challenged with Lipopolysaccharides. Toxins, 15, 394.
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Mot(s) Clé(s)
Porc en croissance
Résumé
Deoxynivalenol (DON) contamination in pig feed ingredients can disrupt vitamin D, calcium, and phosphorus metabolism, thus leading to a decreased growth performance, increased bone mineralization, and a downregulation in the expression of genes related to Ca and P intestinal absorption and renal reabsorption. However, adding vitamin D supplementation during DON challenge, particularly 25-OH-D3, did not mitigate these effects, but it did increase the immune response in piglets facing a lipopolysaccharide challenge.
